We are one of five WHO Collaborating Centres for Reference and Research on Influenza that analyse specimens and virus isolates from influenza patients around the globe. Throughout the year we collect and analyse human influenza viruses for epidemiological, antigenic (immune response) and genetic characteristics. Data from all five Collaborating Centres are reviewed to determine which circulating influenza strains are predominant in the community and therefore would be appropriate components of seasonal vaccines. Twice a year WHO makes a recommendation based on these data on influenza strains to be included in the vaccine for the coming influenza season in the northern hemisphere (recommendation made in February) and the southern hemisphere (recommendation made in September). The final decision on the composition of vaccines in each country is the responsibility of relevant national authorities.

In addition to surveillance, our staff at the Influenza Centre also engage in research, training and education activities. More detailed information about our centre activities can be found here.

Terms of Reference (2007-2011):

1. to obtain and preserve representative strains from outbreaks and sporadic cases of influenza, fully characterise their antigenic properties and distribute them to research and production laboratories;
2. to exchange information and new antigenic variants of influenza viruses with the WHO Collaborating Centres for Reference and Research on Influenza in Atlanta, London and Tokyo;
3. to advise which strains should be included in influenza vaccines;
4. to arrange training of research workers in specialized techniques for isolation, diagnosis and studies of influenza virus;
5. to collect epidemiological information on the prevalence of influenza, especially in countries and areas in the Region; and
6. to assist WHO and national health authorities in developing plans on how to respond to pandemic influenza and to undertake work programmes which will improve the pandemic response